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Clinical outcomes of sirolimus-eluting stenting after rotational atherectomy.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Tamekiyo, Hiromichi Hayashi, Yasuhiko Toyofuku, Mamoru Ueda, Hironori Sakuma, Tadamichi Okimoto, Tomokazu Otsuka, Masaya Imazu, Michinori Kihara, Yasuki |
| Copyright Year | 2009 |
| Abstract | BACKGROUND The efficacy of drug-eluting stents after rotational atherectomy (ROTA) has not been clarified. METHODS AND RESULTS The 704 consecutive patients who underwent percutaneous coronary intervention (PCI) with a sirolimus-eluting stent (SES) (79 with and 625 without ROTA) were enrolled. The 2-year clinical outcome of these patients was compared with that of a group of 1,123 consecutive patients treated with bare-metal stents (BMS) (144 with and 979 without ROTA). At 2 years after index PCI, the use of SES after ROTA was associated with a lower crude incidence of major adverse cardiac events (MACE) than were BMS after ROTA (30.1% vs 43.1%, P=0.024). The difference was mainly derived from the reduction in target lesion revascularization (TLR) (25.0% vs 39.1%, P=0.022). After adjusting for confounders, ROTA-SES was associated with a reduction in MACE and TLR, with a similar hazard ratio to the non-ROTA group only with SES implantation. In a subgroup of dialysis patients, the incidence of TLR after ROTA with SES and BMS was similarly high. CONCLUSIONS The use of SES after ROTA is an appropriate method for selected hard lesions, but has a limited effect in dialysis patients, even after lesion preparation with ROTA. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/circj/73/11/73_CJ-09-0245/_pdf |
| PubMed reference number | 19749479v1 |
| Volume Number | 73 |
| Issue Number | 11 |
| Journal | Circulation journal : official journal of the Japanese Circulation Society |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Artificial cardiac pacemaker Diethylstilbestrol Drug-Eluting Stents KRT17 wt Allele Patients Percutaneous Coronary Intervention Rotational Atherectomy Sirolimus Stent Device Component Stent, device Subgroup A Nepoviruses revascularization |
| Content Type | Text |
| Resource Type | Article |
