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Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ye, Xudong Al-Babili, Salim Klöti, Andreas Zhang, Jingkun Lucca, Paola Beyer, Peter Potrykus, Ingo |
| Copyright Year | 2000 |
| Abstract | Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.goldenrice.org/PDFs/Ye_et_al_Science_2000.pdf |
| Alternate Webpage(s) | http://www.uniroma2.it/didattica/FisiolBiotecVeg/deposito/Golden_rice_.Ye_et_al..pdf |
| PubMed reference number | 10634784v1 |
| Volume Number | 287 |
| Issue Number | 5451 |
| Journal | Science |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | 7-dehydrocholesterol Anabolism Beta Carotene Biosynthetic Pathways Carotenoids Dermox Endosperm Nutrients Provitamin D2 Compound [EPC] Provitamins Staple Device Component Vitamin A Deficiency |
| Content Type | Text |
| Resource Type | Article |