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Randomized Trial Reveals that Physical Activity and Energy Expenditure are associated with Weight and Body Composition after RYGB
| Content Provider | Semantic Scholar |
|---|---|
| Author | Carnero, Elvis Alvarez Hickner, Robert C. Hames, Kazanna Calais Jakicic, John M. Houmard, Joseph A. Coen, Paul M. Goodpaster, Bret H. |
| Copyright Year | 2017 |
| Abstract | OBJECTIVE This study investigated the associations of both physical activity time (PA) and energy expenditure (EE) with weight and fat mass (FM) loss in patients following Roux-en-Y gastric bypass (RYGB) surgery. METHODS Ninety-six nondiabetic patients were included in this analysis. Post-RYGB patients were randomized in one of two treatments: A 6-month exercise training program (RYBG+EX) or lifestyle educational classes (RYGB). Body composition was assessed by dual-energy X-ray absorptiometry and computed tomography. Components of PA and EE were quantified by a multisensory device. Dose-response relationships of both PA and EE with weight loss and body composition were explored according to quartiles of change in steps per day. RESULTS Patients in the highest quartiles of steps per day change lost more FM (3rd = -19.5 kg and 4th = -22.7 kg, P < 0.05) and abdominal adipose tissue (4th = -313 cm2 , P < 0.05), maintained skeletal muscle mass (3rd = -3.1 cm2 and 4th = -4.5 cm2 , P < 0.05), and had greater reductions in resting metabolic rate. Decreases in sedentary EE and increases in light EE and age were significant predictors of both Δweight and ΔFM (R2 = 73.8% and R2 = 70.6%, respectively). CONCLUSIONS Nondiabetic patients who perform higher, yet still modest, amounts of PA following RYGB have greater energy deficits and lose more weight and FM, while maintaining higher skeletal muscle mass. |
| Starting Page | 1206 |
| Ending Page | 1216 |
| Page Count | 11 |
| File Format | PDF HTM / HTML |
| PubMed reference number | 28558160v1 |
| Alternate Webpage(s) | https://doi.org/10.1002/oby.21864 |
| DOI | 10.1002/oby.21864 |
| Journal | Obesity |
| Volume Number | 25 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Abdominal Fat Adipose tissue Body Composition Carotid Body Paraganglioma Diagnostic radiologic examination Dual Dual-Energy X-Ray Absorptiometry Energy Metabolism Exercise Fat embolism (disorder) Hearing Loss, High-Frequency How Often Weight Loss Mental association Patients Platelet Glycoprotein 4, human Rest Roux-en-Y Anastomosis Stomach Neoplasms Training Programs X-Ray Computed Tomography bypass |
| Content Type | Text |
| Resource Type | Article |
