NDLI: Lewis Acid Mediated Cyclizations: Diastereoselective Synthesis of Six- to Eight-Membered Substituted Cyclic Ethers.

Content Provider	Semantic Scholar
Author	Ghosh, Arun K. Tomaine, Anthony J. Cantwell, Kelsey E.
Copyright Year	2017
Abstract	Cyclic ethers are widely abundant in natural products. Cyclic ether templates are also utilized in drug design and medicinal chemistry. Although the synthetic processes for this class of compounds have been studied extensively with respect to five- and six-membered rings, medium-sized cyclic ethers are synthetically more challenging due to a variety of factors. Herein, we report our results on the Lewis acid catalyzed synthesis of medium-sized cyclic ethers in a diastereoselective manner.
Starting Page	4229
Ending Page	4246
Page Count	18
File Format	PDF HTM / HTML
DOI	10.1055/s-0036-1589054
PubMed reference number	29983455
Journal	Medline
Volume Number	49
Issue Number	18
Alternate Webpage(s)	https://www.thieme-connect.com/media/synthesis/201718/supmat/sup_ss-2017-c0259-st_10-1055_s-0036-1589054.pdf
Alternate Webpage(s)	https://doi.org/10.1055/s-0036-1589054
Journal	Synthesis
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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