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Growth factors in the pathogenesis of diabetic foot ulcers.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Qi, Min Zhou, Qiuhong Zeng, Weiqi Wu, Lisha Zhao, Shuang Chen, Wangqing Luo, Chang Shen, Minxue Zhang, Jianglin Tang, Can- |
| Copyright Year | 2018 |
| Abstract | Foot ulcers affect 15% of patients with diabetes, resulting in a great health burden. The occurrence and development of diabetic foot ulcers is associated with neuropathy, peripheral arterial disease, and infection. Several growth factors are involved in these processes, including epidermal growth factor, vascular endothelial growth factor, transforming growth factor-beta, fibroblast growth factor, and erythropoietin, which could promote wound healing of patients with diabetes. Thus, this review discusses the role of these growth factors in the pathogenesis of diabetic foot ulcers, aiming to achieve novel insights into the management of diabetic foot ulcers. |
| Starting Page | 310 |
| Ending Page | 317 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.bioscience.org/fbs/getfile.php?FileName=/2018/v23/af/4593/4593.pdf |
| PubMed reference number | 28930549v1 |
| Volume Number | 23 |
| Journal | Frontiers in bioscience |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Arteriopathic disease Diabetes Mellitus Diabetic foot ulcer Endothelial Growth Factors Fibroblast Growth Factor Patients Peripheral Neuropathy Transforming Growth Factor beta Transforming Growth Factors Wound Healing nervous system disorder |
| Content Type | Text |
| Resource Type | Article |