NDLI: Metastatic colorectal cancer--what about the primary?

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Metastatic colorectal cancer--what about the primary?

Content Provider	Semantic Scholar
Author	Popescu, Irinel Alexandrescu, Sorin Tiberiu
Copyright Year	2012
Abstract	BACKGROUND Approximately 25% of patients with colorectal cancer present synchronous metastases, most frequently located in the liver. AIMS The assessment of optimal therapeutic strategies for the primary tumor in such patients. METHODS We analyzed the outcomes of 209 patients who underwent simultaneous or delayed resection of the primary tumor and liver metastases, the survival rates of patients with initially unresectable liver metastases that were rendered resectable, and the prognostic factors related to the primary tumor. RESULTS The outcomes of simultaneous resections were similar to those of delayed resection. In patients with initially unresectable liver metastases that were rendered resectable, the survival rates were similar to those of patients with initially resectable metastases. The survival rate of N2 patients was significantly lower than those of N1 and N0 patients. CONCLUSIONS Simultaneous resection provides a safety profile and survival rate similar to that of delayed resection. The N category allows for prognostic estimation in metastatic colorectal patients.
Starting Page	47
Ending Page	55
Page Count	9
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.doiserbia.nb.rs/(A(EhtvHw_i0gEkAAAAYjNmZmNhM2EtNGNlZi00NzRhLWJmOTQtODUwZmY3YjI2YjgzSWhoZPwk_ybI2pZGjTkIQqZoNxA1))/img/doi/0354-950X/2012/0354-950X1202047P.pdf
PubMed reference number	23373358v1
Volume Number	59
Issue Number	2
Journal	Acta chirurgica Iugoslavica
Language	English
Access Restriction	Open
Subject Keyword	Biomarkers, Tumor Colorectal Carcinoma Excision Liver diseases Neoplasm Metastasis Neoplasms Neoplasms, Multiple Primary Patients liver metastases pediatric intracranial germ cell brain tumor primary tumor unresectable
Content Type	Text
Resource Type	Article

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