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Synthesis, Characterization and Antimicrobial Activities of Some Fluorine Containing 2‐(1‐Phenyl‐3‐aryl‐1H‐pyrazol‐4‐yl)‐3‐chlorochromones, 2‐(1‐Phenyl‐3‐aryl‐1H‐pyrazol‐4‐yl)chromones and 5‐(1‐Phenyl‐3‐aryl‐1H‐pyrazol‐4‐yl)‐3‐ (2‐hydroxyphenyl)‐4,5‐dihydropyrazolines.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Joshi, Neeta S. Shaikh, Abdulla A. Deshpande, Abhijit P. Karale, Bhausaheb K. Bhirud, Shekar Bhaskar Gill, Charansingh H. |
| Copyright Year | 2005 |
| Abstract | Base catalyzed condensation of 1 with 2 gives compound 3 [1-(5-fluoro-2-hydroxyphenyl)-3-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-2-propen-1-one]. On oxidative cyclization with DMSO-CuCl 2 3 gives 2-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-3-chloro-6-fluorochromones 4. On cyclization with DMSO-I 2 , 3 gives 2-(1-phenyl-3-aryl-lH-pyrazol-4-yl)- 6-fluorochromones 5. When 3 is heated with hydrazine in dioxane gives 6 [5-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-3-(5-fluoro-2-hydroxyphenyl)-4,5-dihydropyrazolines. The products 3, 4, 5 and 6 are characterized by spectral and elemental analysis. Compounds 3, 4 and 6 are tested for their antimicrobial activities. |
| Starting Page | 422 |
| Ending Page | 425 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/chin.200524115 |
| Volume Number | 36 |
| Alternate Webpage(s) | http://nopr.niscair.res.in/bitstream/123456789/8943/1/IJCB%2044B(2)%20422-425.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/chin.200524115 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |