NDLI: Assessment of coronary microcirculation in patients with takotsubo-like left ventricular dysfunction.

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Assessment of coronary microcirculation in patients with takotsubo-like left ventricular dysfunction.

Content Provider	Semantic Scholar
Author	Kume, Teruyoshi Akasaka, Takashi Kawamoto, Takahiro Yoshitani, Hidetoshi Watanabe, Nozomi Neishi, Yoji Wada, Nozomi Yoshida, Kiyoshi
Copyright Year	2005
Abstract	BACKGROUND The precise mechanism of takotsubo-like left ventricular (LV) dysfunction remains unclear. METHODS AND RESULTS Eight consecutive patients with takotsubo-like LV dysfunction were studied. In the acute phase and 3 weeks later, the coronary flow velocity spectrum and coronary flow velocity reserve (CFVR) were recorded by Doppler guidewire. The deceleration time of diastolic velocity (DDT; ms) was measured from the peak diastolic velocity to the point where the extrapolated line intersected the baseline. In all cases, CFVR of the 3 coronary arteries increased during follow-up (1.7+/-0.5 to 2.4+/-0.5 for the left anterior descending artery (p < 0.05), 1.7+/-0.5 to 2.7+/-0.8 for the left circumflex artery (p < 0.05) and 1.7+/-0.3 to 2.5+/-0.4 for the right coronary artery (p < 0.05)). In addition, the DDT of all coronary arteries increased during follow-up. CONCLUSIONS Decreased CFVR and short DDT were demonstrated in patients with takotsubo-like transient LV dysfunction in the acute phase, and these findings improved 3 weeks later, which suggests that coronary microvascular dysfunction may be a causative mechanism.
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.jstage.jst.go.jp/article/circj/69/8/69_8_934/_pdf
PubMed reference number	16041162v1
Volume Number	69
Issue Number	8
Journal	Circulation journal : official journal of the Japanese Circulation Society
Language	English
Access Restriction	Open
Subject Keyword	Anterior descending branch of left coronary artery Coronary Arteriosclerosis DDT (Insecticide) Deceleration Diastole Erectile dysfunction Follow-Up Report Guidewire Device Component Microcirculation Patients Physiological Sexual Disorders Right coronary artery structure Structure of circumflex branch of left coronary artery Ventricular Dysfunction Ventricular Dysfunction, Left
Content Type	Text
Resource Type	Article

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