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Participation in International and Trials of ABC ATLAS Adjuvant Treatment for Breast Cancer: An Inspiring Clinical Research Experience
| Content Provider | Semantic Scholar |
|---|---|
| Author | Haddad, Peiman |
| Copyright Year | 2015 |
| Abstract | Iranian cancer specialists generally have a great interest in clinical research carried out in international settings, but participation in large multicenter clinical trials that include other countries is often difficult to arrange. In this regard, two of the most successful endeavors in Iran are the Adjuvant Breast Cancer ( ) and Adjuvant Tamoxifen: ABC LongerAgainst Shorter ( ) trials. ATLAS In late 1992, Prof. John Yarnold and his team in the United Kingdom ( ) Institute of Cancer UK Research ( ) initiated the ( ) trial to assess ICR ABC overall survival and other long-term outcomes of combined modality therapy for women with early breast cancer. The chemotherapy side of the ABC Trial tested the addition of chemotherapy to prolonged tamoxifen (with or without elective ovarian ablation or suppression), and the ovarian ablation or suppression side of the trial assessed the addition of ovarian ablation or suppression to prolonged tamoxifen (with or without elective chemotherapy). From the very beginning, Prof. Yarnold sought collaboration with many countries, and received a positive response from Iran through the efforts of Prof. Kamaleddin Dehshiri and Prof. Jahangir Rafat (Cancer Institute, Tehran University of Medical Sciences) and also Professor Seyed-Hossein Mortazavi, (Jorjani Hospital, Shahid Beheshti University of Medical Sciences). Subsequently, after the start of the trial in Iran i.e. in 1993 and under the leadership of these esteemed professors, other colleagues including the author of this editorial joined the trial ( Trial collaboraABC tors from Iran, as listed in Trial reports ABC published, were K. Dehshiri, P. Haddad, F. Amouzgar-Hashemi, S.H. Mortazavi, B. Shahrad, M. Shahidi). 3,4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.archbreastcancer.com/index.php/abc/article/download/24/108 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |