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Long-term follow-up on a large cohort of "full-metal jacket" percutaneous coronary intervention procedures.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sharp, Andrew S. P. Latib, Azeem Ielasi, Alfonso Larosa, Claudio Godino, Cosmo Saolini, Marta Magni, Valeria Gerber, Robert T. Montorfano, Matteo Carlino, M. Eugenia Michev, Iassen Chieffo, Alaide Colombo, A. |
| Copyright Year | 2009 |
| Abstract | BACKGROUND Limited long-term data exist on patients who have undergone drug-eluting stenting of very long lesions (requiring >or=60 mm of continuous stent) in native coronary arteries ("full-metal jacket"). METHODS AND RESULTS We examined consecutive procedures taking place between March 2002 and 2007 at 2 high-volume centers in Milan, Italy. Exclusion criteria were percutaneous coronary intervention for restenosis, percutaneous coronary intervention to a bypass graft, or percutaneous coronary intervention for acute ST-elevation myocardial infarction (MI). We identified 658 full-metal jacket lesions in 617 patients. Average age of the cohort was 62.0+/-10.6; 32.8% were diabetic, 51.5% had a previous MI, and 33.4% had undergone a previous percutaneous transluminal coronary angioplasty. Mean ejection fraction was 52.1+/-10.4%. The lesion was a chronic total occlusion in 33.0%. Median duration of clinical follow-up was 39 months (interquartile range, 28 to 50). Six-month follow-up was achieved in 97% of patients; 2-year follow-up was achieved in 91%. All-cause mortality rate was 7.3%; cardiac death rate was 3.6%. Non-procedure-related MI rates were 3.5%. Target lesion revascularization rates were 23.4%. There were 17 cases of Academic Research Consortium-defined definite or probable stent thrombosis (2.6%): 5 acute, 2 subacute, 6 late, and 4 very late. Ten of the 17 cases occurred while the patient was receiving dual antiplatelet therapy; 4 of the 17 after premature termination of 1 or both antiplatelets, and 3 of the 17 occurred while the patient was receiving single-antiplatelet therapy, after having completed the prescribed course of dual antiplatelet therapy. CONCLUSIONS When very long lesions (>or=60 mm) were treated using overlapping drug-eluting stents, 23.4% required a further procedure for restenosis at 3-year follow-up. However, MI, stent thrombosis, and cardiac mortality rates were relatively low. |
| Starting Page | 391 |
| Ending Page | 394 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://circinterventions.ahajournals.org/content/circcvint/2/5/416.full.pdf |
| PubMed reference number | 20031751v1 |
| Alternate Webpage(s) | https://doi.org/10.1161/CIRCINTERVENTIONS.109.886945 |
| DOI | 10.1161/circinterventions.109.886945 |
| Journal | Circulation. Cardiovascular interventions |
| Volume Number | 2 |
| Issue Number | 5 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cardiac Death Coronary Artery Disease Diabetes Mellitus Drug-Eluting Stents Dual Ejection fraction (procedure) Follow-Up Report Mortality Vital Statistics Myocardial Infarction Patients Percutaneous Coronary Intervention Percutaneous Transluminal Coronary Angioplasty Probability Stent Device Component Stent, device Thrombosis Transplanted tissue restenosis revascularization |
| Content Type | Text |
| Resource Type | Article |
