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De l'immunité innée à l'immunité adaptative : Un continuum
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fougereau, Michel |
| Copyright Year | 2007 |
| Abstract | By the end of the nineteenth century, after what is generally referred to as the Pastorian revolution, there were two opposing visions of immunity: that of the German school with Paul Ehrlich, based on the dominating role of circulating antibodies, and that of the French (or Franco-Russian) school, with Elie Metchnikoff and phagocytosis. In reality, these two conceptions cover two aspects of body defences, which were opposed for a very long time as adaptive immunity (antibodies and later on cellular immunity with T lymphocytes), and innate immunity (phagocytosis and NK cells). Following the much more recent hypotheses of Charles Janeway, these notions literally exploded with the identification of defence mechanisms in invertebrates. As is often the case, both innate and adaptive immunity were found to be closely associated in a unified physiology of the immune system, one of the most fascinating fields (with the central nervous system) in higher vertebrates. This communication reviews this complex topic. |
| Starting Page | 181 |
| Ending Page | 189 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| DOI | 10.4267/2042/47883 |
| Volume Number | 160 |
| Alternate Webpage(s) | http://academieveterinaire.free.fr/academie/fougereau.pdf |
| Alternate Webpage(s) | https://www.academie-veterinaire-defrance.org/fileadmin/user_upload/Bulletin/pdf/2007/numero03/181.pdf |
| Alternate Webpage(s) | https://doi.org/10.4267/2042%2F47883 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
