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Dissipative particle dynamics simulation on paclitaxel loaded PEO-PPO-PEO block copolymer micelles.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wang, Zhigao Jiang, Jie |
| Copyright Year | 2014 |
| Abstract | Self-assembly behavior of the polymer drug loading micelle PEO-PPO-PEO was studied using dissipative particle dynamics (DPD) simulation method with various simulation steps. The distributions of drugs in polymer carriers were also investigated with different drug feed ratios. Polymer carriers distributed on the surface of the spherical micelle, and drugs were almost encapsulated in the inner of the micelle. Our simulation work demonstrates that the DPD simulation is effective to study the drug loaded systems and can give useful guidance on the design and preparation of new drug carriers with tailored properties. |
| File Format | PDF HTM / HTML |
| DOI | 10.1166/jnn.2014.8468 |
| PubMed reference number | 24745277 |
| Journal | Medline |
| Volume Number | 14 |
| Issue Number | 3 |
| Alternate Webpage(s) | http://hgycg.cdut.edu.cn/data/upload/1563443808710.pdf |
| Alternate Webpage(s) | https://doi.org/10.1166/jnn.2014.8468 |
| Journal | Journal of nanoscience and nanotechnology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
