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Genome-wide differentially methylated genes associated with post-traumatic stress disorder in female rape survivors
| Content Provider | Semantic Scholar |
|---|---|
| Author | Nöthling, Jani Seedat, Soraya Abrahams, Naeemah Hemmings, Sian Megan Joanna |
| Copyright Year | 2018 |
| Abstract | Copyright: © 2018. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. Introduction: Alterations to the epigenome in response to psychological trauma have been reported as a mechanism mediating gene and environmental interaction. Differentially methylated genes involved in the biological pathways associated with the adverse phenotypic behavioural presentations in post-traumatic stress disorder (PTSD) have previously been identified. However, the majority of studies have focussed on differential methylation of single candidate genes in participants exposed to heterogeneous index traumas. The objective of this study was to identify genome-wide differences in methylation profiles of a group of women exposed to rape, with and without PTSD. |
| File Format | PDF HTM / HTML |
| PubMed reference number | 6191739 |
| Volume Number | 24 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Brassica rapa Candidate Disease Gene Copyright Differential Diagnosis Differential Methylation Genetic Heterogeneity Post-Traumatic Stress Disorder Psychological Trauma Stress Disorders, Traumatic Survivors Traumatic injury |
| Content Type | Text |
| Resource Type | Article |
