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Reviewer ' s report Historical Trends in Survival of Hospitalized Heart Failure Patients : 2000 versus 1995 Title : 1 18 October 2006 Version : Date :
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sanderman, Robbert |
| Copyright Year | 2006 |
| Abstract | a. Prescription of digitalis. This is very important, especially for women, as posthoc analysis in the DIG trial has shown that digitalis (in certain blood concentrations) might increase mortality in women, but not in men. Previous studies have shown that prescription of digitalis has decreased after the publication of the DIG trial (1997), yet this might explain (among others) why mortality rates did not change significantly in women. b. Prescription of other classes of medication that were proved to increase mortality, such as class I antiarrhythmic agents or first generation Calcium-channels blockers. The prescription of these agents also decreased between 1990-2000. c. A comorbidity score would have captured better the disease severity, especially that half of the patients missed the LVEF measurement. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://static-content.springer.com/openpeerreview/art:10.1186%2F1471-2261-7-2/12872_2006_2_ReviewerReport_V1_R2.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
