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Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Shibata, Masunari Yamada, Shingo Kumar, Senthil R. Calero, Miguel Bading, James R. Frangione, B. F. Holtzman, David M. Miller, Christopher Allen Strickland, Dudley K. Ghiso, Jorge Zlokovic, Berislav V. |
| Copyright Year | 2000 |
| Abstract | Elimination of amyloid-ss peptide (Ass) from the brain is poorly understood. After intracerebral microinjections in young mice, (125)I-Ass(1-40) was rapidly removed from the brain (t(1/2) |
| Starting Page | 132 |
| Ending Page | 132 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://dm5migu4zj3pb.cloudfront.net/manuscripts/10000/10498/JCI0010498.pdf |
| PubMed reference number | 11120756v1 |
| Alternate Webpage(s) | https://doi.org/10.1172/JCI10498 |
| DOI | 10.1172/JCI10498 |
| Journal | The Journal of clinical investigation |
| Volume Number | 106 |
| Issue Number | 12 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Alzheimer's Disease Amino Acids Amyloid beta-Peptides Apolipoprotein E Apolipoproteins Blood - brain barrier anatomy Cerebrovascular Disorders Down-Regulation Interstitial Fluid Metabolic Process, Cellular Microinjections Microvessels Patients Peptide PHI Small Traumatic cerebral hemorrhage |
| Content Type | Text |
| Resource Type | Article |