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The Relationship between End Tidal Carbon Dioxide and Arterial Carbon Dioxide during Controlled Hypotensive Anaesthesia
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ali, Syed Shujat Dubikăitis, A. Iu Qattan, Abdul Raheem Al |
| Copyright Year | 2002 |
| Abstract | Objectives: To prospectively assess the magnitude of changes in the arterial-to-end tidal carbon dioxide gradient [P(a-ET)CO2] as well as in the ratio of physiological dead space to tidal volume (Vdphys/Vt) during controlled hypotensive anaesthesia, and to evaluate whether or not ventilatory requirements remain unaltered during this procedure. Subjects and Methods: Twelve adult patients with American Society of Anesthesiologists’ physical status I and II undergoing middle ear surgery were selected. A standard anaesthetic procedure was followed for all cases, using thiopental sodium, succinylcholine, fentanyl, atracurium and 60% N2O in 40% oxygen supplemented with isoflurane. Mean arterial blood pressure (MAP) was reduced to 60 ± 5 mm Hg in all patients using a sodium nitroprusside infusion. The end tidal (ET) CO2, PaCO2, MAP, peak airway pressure, plateau pressure and expiratory minute volume were recorded during a period of normal arterial blood pressure (time 1) and during hypotension (time 2). Results: A significant decrease in PaCO2 (7%) and ETCO2 (17%) from time 1 to time 2 (p < 0.01) was noted, as was a significant increase in P(a-ET)CO2 (48%) and in the Vdphys/Vt ratio (41.17%) (p < 0.01) during the same period. Conclusion: The decrease in ETCO2 does not reflect the changes in PaCO2. The larger decrease in ETCO2 is mainly due to the increase in the Vdphys/Vt ratio. During anaesthesia, once normocapnia is achieved with normal arterial blood pressure, there is hardly any need to change the ventilation after initiation of controlled hypotension. |
| Starting Page | 35 |
| Ending Page | 37 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| DOI | 10.1159/000048658 |
| PubMed reference number | 12116693 |
| Journal | Medline |
| Volume Number | 11 |
| Alternate Webpage(s) | https://www.karger.com/Article/Pdf/48658 |
| Alternate Webpage(s) | https://doi.org/10.1159/000048658 |
| Journal | Medical Principles and Practice |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
