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Use of nonsteroidal anti-inflammatory drugs in diabetic retinopathy.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Malukiewicz, Grażyna Stafiej, Joanna Lesiewska, Hanna Sikorski, Bartosz L. |
| Copyright Year | 2016 |
| Abstract | INTRODUCTION Diabetic macular edema, a manifestation of diabetic retinopathy, occurs more frequently in type 2 diabetes mellitus. There is evidence that inflammation plays a prominent role in the pathogenesis. A number of pro-inflammatory cytokines are consistently elevated in the vitreous of patients with advanced stages of diabetic retinopathy. Nonsteroidal anti-inflammatory drugs inhibit the catalytic activity of the cyclooxygenase isoenzymes COX-1 and COX-2, the key enzymes in inflammatory processes. PURPOSE To present current knowledge of benefits and limitations of using nonsteroidal anti-inflammatory drugs in diabetic retinopathy. CONCLUSIONS Nonsteroidal anti-inflammatory druds may be considered as an adjuvant treatment in diabetic retinopathy especially in patients with diabetic macular edema. |
| Starting Page | 44 |
| Ending Page | 47 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.termedia.pl/Journal/-124/pdf-31078-10?filename=KO_01_2016_MALUKIEWICZ_USE.pdf |
| PubMed reference number | 29715408v1 |
| Volume Number | 118 |
| Issue Number | 1 |
| Journal | Klinika oczna |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Angioedema Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Diabetes Mellitus Diabetes Mellitus, Non-Insulin-Dependent Diabetic Retinopathy Inflammatory Bowel Diseases Isoenzymes Macular retinal edema Patients Pharmaceutical Adjuvants Retinal Diseases benefit diabetic macular edema enzyme activity |
| Content Type | Text |
| Resource Type | Article |
