Evaluación de los efectos de la radioterapia preoperatoria en el pronóstico de los pacientes con cáncer de recto bajo

Content Provider	Semantic Scholar
Author	Neto, J. A. Reis Amarillo, Ha Junior, Jose Alfredo Reis Kagohara, Odorino Hideyoshi Neto, Joaquim Simões
Copyright Year	2008
Abstract	Aims: In spite of the new technology stapler, antibiotics, anesthesia and new surgical and diagnostic procedures the prognosis on treatment of the cancer of the rectum has not changed in the last fifty years. Survival rates of 50 to 55% seems immutable in several published series. The main cause for those results is the high incidence of recurrence, either local or widespread. Local recurrence is directly related to the number of undifferentiated cells and to the grade of wall invasion. Widespread recurrence depends specifically on the lymphatic and vascular spreading. So any kind of treatment that would diminish the number of undifferentiated cells and the size or the tumor wall penetration would certainly decrease the local recurrence rate, lengthening the interval free from cancer and, perhaps, modifying the long term survival rate. Between 1978 and 2003, a total of 358 patients with adenocarcinoma of the lower rectum (from the pectinate line to 10 cm above) were treated by preoperative radiotherapy. Methodology: The same protocol was used in all the patients — 400 cGy, 200 cGy/day, during 4 consecutive weeks (anterior and posterior pelvic fields) by Artemisa medigraphic en línea
Starting Page	44
Ending Page	52
Page Count	9
File Format	PDF HTM / HTML
Volume Number	14
Alternate Webpage(s)	http://www.medigraphic.com/pdfs/proctologia/c-2008/c082a.pdf
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article