Experimental vibrational spectroscopic and theoretical (ab initio calculations) studies of the di-amino acid peptide cyclo(L-Val-L-Val)

Content Provider	Semantic Scholar
Author	Mendham, Andrew P. Dines, Trevor J. Withnall, Robert Chowdhry, Babur Z.
Copyright Year	2004
Abstract	The primary focus of our studies is an ongoing research programme examining the experimental and theoretically calculated vibrational spectra (Raman and FT-IR) of cyclic and linear di-amino acid peptides. The Raman spectrum, fig. 2a, of cyclo(L-Val-L-Val) shows a weak, broad band located at 1658 cm assigned to an amide I vibration. It is noticeable that on Ndeuteriation this vibrational band increases in intensity and is shifted down in wavenumber by ~ 43 cm. The deuterium shift is in keeping with other cyclic dipeptides investigated [3, 4] and is probably typical for the N-H contribution to the potential energy distribution of the amide I mode for cyclic dipeptides adopting a cis amide conformation. For example, cyclo(L-Met-L-Met), cyclo(L-Ala-L-Ala) and cyclo(L-Ala-Gly) show an amide I shift of approximately 33, 32 and 39 cm respectively.
Starting Page	482
Ending Page	483
Page Count	2
File Format	PDF HTM / HTML
DOI	10.1071/sa0402226
Volume Number	2
Alternate Webpage(s)	http://www.publish.csiro.au/SA/pdf/SA0402226
Alternate Webpage(s)	https://doi.org/10.1071/sa0402226
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article