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DNA polymorphic loci mapped to human chromosomes 3, 5, 9, 11, 17, 18, and 22.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Naylor, Susan L. Sakaguchi, Alan Y. Barker, David White, R. Shows, T. B. |
| Copyright Year | 1984 |
| Abstract | Using the techniques of Southern filter hybridization and somatic cell genetics, seven genomic DNA fragments recognizing DNA polymorphic loci were mapped to specific chromosomes and regions of chromosomes. The seven probes, isolated from human genomic libraries, lacked repetitive sequences and were hybridized to DNA isolated from a set of human-rodent somatic cell hybrids segregating human chromosomes. These probes detected DNA sequences on human chromosomes 3, 5, 9, 11, 17, 18, and 22. These DNA polymorphic sites, which occur in 10% or greater of the population, will serve as markers for linkage studies with known polymorphic loci as well as to establish linkage with disease loci. |
| File Format | PDF HTM / HTML |
| DOI | 10.1073/pnas.81.8.2447 |
| PubMed reference number | 6585809 |
| Journal | Medline |
| Volume Number | 81 |
| Issue Number | 8 |
| Alternate Webpage(s) | http://www.pnas.org/content/81/8/2447.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1073/pnas.81.8.2447 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |