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Quantifizierung motorischer Fatigue durch Bewegungsanalyse : Entwicklung und Evaluation eines neuen Diagnostikverfahrens bei Patienten mit Multipler Sklerose
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sehle, Aida |
| Copyright Year | 2015 |
| Abstract | Motor fatigue is one of the most common and disabling symptom in patients with multiple sclerosis. Despite the high incidence of this symptom and its serious consequences for the patients, no instruments or methods that could detect the motor fatigue objectively have been developed. The present work concentrates on the development and testing of a method for objective measurement of motor fatigue among patients with multiple sclerosis and after stroke. This dissertation is a cumulative work consisting of three empirical studies. The first study develops and tests a new method to quantify changes in gait patterns among healthy volunteers. The properties of the limit cycle attractor were used in this study. This method identifies changes in movement patterns, that is, changes in gait characteristic and gait variability, in individuals both at the group and at the individual level. In the second study, the newly developed method was used to quantify motor fatigue among patients with multiple sclerosis. More specifically, in this context, the Fatigue index Kliniken Schmieder was developed for an objective detection of motor fatigue. Using this index, for the first time, changes in gait patterns due to the acute motor fatigue could be detected in patients with multiple sclerosis. In addition, the limits which allowed a clear diagnosis of motor fatigue were calibrated. Furthermore, it was demonstrated that motor fatigue is not related to muscle fatigue. In the third study, the Fatigue index Kliniken Schmieder was successfully used to measure motor fatigue among stroke patients. This allowed for a unique comparison of motor fatigue between stroke patients and patients with multiple sclerosis on the basis of empirical data. Our results show that stroke patients display similar degrees of motor fatigue as patients with multiple sclerosis. The Fatigue index Kliniken Schmieder proved to be robust with respect to chronic walking impairments. Fatigue Index Kliniken Schmieder erwies sich als robust gegenüber bereits be-stehenden chronischen Gangbeeinträchtigungen. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://kops.uni-konstanz.de/bitstream/handle/123456789/32171/Sehle_0-308197.pdf?isAllowed=y&sequence=5 |
| Alternate Webpage(s) | https://kops.uni-konstanz.de/bitstream/handle/123456789/32171/Sehle_0-308197.pdf?isAllowed=y&sequence=5 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
