Loading...
Please wait, while we are loading the content...
Similar Documents
Hypocholesterolemic effect of hot-water extract from mycelia of Cordyceps sinensis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Koh, Jason Jae Hyun Kim, Jin-Man Chang, Un-Jae Suh, Hyung Joo |
| Copyright Year | 2003 |
| Abstract | This study was conducted to investigate the hypocholesterolemic effect of the hot-water fraction (HW) from cultured mycelia of Cordyceps sinensis in a 5 l fermenter. The composition of HW was mainly carbohydrate (83.9%) and protein (11.8%) on a dry basis, and the carbohydrate of HW consisted of glucose, mannose, galactose, and arabinose in the molecular ratio of 1.0 : 0.8 : 0.5 : 0.1, respectively. In mice fed a cholesterol-free diet and those fed a cholesterol-enriched diet, body and liver weights were not significantly different from those of the controls. The serum total cholesterol (TC) of all mice groups administered HW (150 and 300 mg/kg/d, respectively) with the cholesterol-enriched diet decreased more than in the control group. Among the mice fed the cholesterol-enriched diet, HW also increased the high-density lipoprotein (HDL) cholesterol level, but decreased the very low-density lipoprotein plus low-density lipoprotein (VLDL+LDL) cholesterol level. The changes in HDL- and VLDL+LDL-cholesterol levels consequently decreased the atherogenic value. The results indicate that HW in rats administered a cholesterol-enriched diet decreased the plasma cholesterol level. The 300 mg/kg dose had a significant effect on the serum TC level. |
| Starting Page | 83 |
| Ending Page | 94 |
| Page Count | 12 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.invitehealth.com/media/pdf/hypocholesterolemic-effect-of-hot-water-extract-from-mycelia-of-cordyceps.pdf |
| PubMed reference number | 12520179v1 |
| Volume Number | 26 |
| Issue Number | 1 |
| Journal | Biological & pharmaceutical bulletin |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Arabinose Carbohydrates Cholesterol Control Groups Cordyceps sinensis (fungus) Galactose Glucose High Density Lipoproteins Low-Density Lipoproteins Milligram per Kilogram per Day Weight mg/kg |
| Content Type | Text |
| Resource Type | Article |
