NDLI: Role of Total Mesorectal Excision in Curative Resection of Rectal Cancer

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Role of Total Mesorectal Excision in Curative Resection of Rectal Cancer

Content Provider	Semantic Scholar
Author	Baoming, Y. U. Donghua, L. I.
Copyright Year	2002
Abstract	Objective To evaluate the effect of total mesorectal excision (TME) on local recurrence rate and 5-year survival rate following radical resection for rectal cancer. Methods From Jan. 1991 to Dec. 1998, 746 cases of rectal cancer treated with radical resection were divided randomly into group B (341 cases) undergoing traditional prCmedures and group A (405 cases) undergoing TME. There was no significant difference in tumor location, morphological appearance, histological patterns, grade of differentiation and staging clssification between two groups. SSR was carried out in 65.25% cases of group A and 54.25% cases in group B (P < 0.05). Results Operative death occurred in 9 cases with an operative mortality rate being 0.97% , 5 cases in group A and 4 cases in group B. Anastomotic leakage occurred in 19 cases with an occurrence rate being 4.21% , 8 in group A (3.95%) and 11 cases in group B (5 .95%). The follow-up rate in this series was 91% with the follow-up duration from 2 to 9 years, mean 48.3 months. l~ocal recurrence occurred in 47 eases with an overall recurrence rate [seing 6.30% , 16 eases in group A (3 .95%) and 31 in group B (9.09%) , P < 0.01. The overall 5year survival rate was 72.46% • 3.84% ( life table method) , 78.58% + 3.28% in group A and 67.86% +3.02 % in group B. respectively, P<0.05. Conclusion Radical resection with TME can effectively reduce the local recurrence tale and significantly improve 5year survival rate as compared with traditional procedures.
Starting Page	126
Ending Page	128
Page Count	3
File Format	PDF HTM / HTML
Volume Number	1
Alternate Webpage(s)	https://page-one.springer.com/pdf/preview/10.1007/BF02851703
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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