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Sclerosing Angiomatoid Nodular Transformation (SANT) in Spleen - A Case Report -
| Content Provider | Semantic Scholar |
|---|---|
| Author | Lee, Hyun Jung Choi, Song-Yi Huang, Song Mei Sul, Ji-Young Kim, Jin-Man |
| Copyright Year | 2011 |
| Abstract | Sclerosing angiomatoid nodular transformation (SANT) of spleen is a rare inflammatory tumor-like vascular lesion composed of angiomatoid nodules in a fibrosclerotic background. We report here - in on a case of SANT in the spleen with its pathologic features, and review the related literature. A 50-year-old woman presented with mild left upper quadrant discomfort and tenderness and she showed a 6 cm-sized solitary splenic mass on computed tomography. She underwent laparo- scopic splenectomy. Grossly, the spleen showed a well circumscribed round-shaped solid mass with multinodular hemorrhagic surfaces. Microscopically, the mass consisted of multiple angio- matoid nodules surrounded by collagen bundles with fibroblasts and a lymphoplasma cell infiltra - tion. Immunohistochemically, the cells of the angiomatoid nodules were positive for CD31, CD30, CD34, alpha-smooth muscle actin, and VWF-VIII, but they were negative for CD8, anaplastic lym- phoma kinase protein, and D2-40. The patient has been under close follow-up without recur- rence. |
| Starting Page | 111 |
| Ending Page | 111 |
| Page Count | 1 |
| File Format | PDF HTM / HTML |
| DOI | 10.4132/koreanjpathol.2011.45.1.111 |
| Volume Number | 45 |
| Alternate Webpage(s) | http://koreanjpathol.org/upload/journal/kjp-45-111.pdf |
| Alternate Webpage(s) | https://doi.org/10.4132/koreanjpathol.2011.45.1.111 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
