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Comparison of Prognosis in Types 1 and 2 Papillary Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma in T1 Stage
| Content Provider | Semantic Scholar |
|---|---|
| Author | Lee, Jaehoon Chae, Han Kyu Lee, Wonchul Nam, Wook Lim, Bumjin Choi, Se Young Kyung, Yoon Soo You, Dalsan Song, Cheryn Bumsik Hyuk, Jun Ahn, Hanjong Kim, Choung-Soo |
| Copyright Year | 2018 |
| Abstract | Purpose: We compared subtypes of papillary renal cell carcinoma (pRCC; types 1 and 2) and clear cell renal cell carcinoma (ccRCC) in patients with T1-stage RCC to analyze the impact of the subtype on oncological outcomes. Materials and Methods: This paper reviewed 75 patients with pRCC and 252 patients with ccRCC at T1-stage from 1998–2012. Thus, we assessed the impact of subtype on oncologic outcomes among patients with T1-stage RCC. We used Kaplan-Meier analysis to estimate the overall survival and recurrence-free survival The median follow-up duration was 95 months (interquartile range, 75.4–119.3 months). Results: The 5-year recurrence-free survivals of pRCC and ccRCC were 95.4% and 97.6%, respectively. pRCC is worse than ccRCC in terms of recurrence-free survival (p=0.008) and there was no significant difference in the overall survival between pRCC and ccRCC (p=0.32). In addition, there was no significant statistical difference between type 1 pRCC and type 2 pRCC in terms of either recurrence-free survival (p=0.526) or overall survival (p=0.701). Age (hazard ratio [HR], 1.069; p<0.001) and recurrence (HR, 4.93; p<0.001) were predictors of overall survival. Only tumor size (HR, 1.071; p=0.004) was predictors in the case of cancer specific survival in the multivariate analysis. Conclusions: Among patients with T1-stage RCC, recurrence after surgery was more common in pRCC than ccRCC. The subtype of pRCC (types 1 and 2) had no impact on the recurrence-free survival or overall survival. (Korean J Urol Oncol 2018;16:119-125) |
| Starting Page | 119 |
| Ending Page | 125 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Volume Number | 16 |
| Alternate Webpage(s) | https://www.kjuo.or.kr/upload/pdf/kjuo-16-3-119.pdf |
| Alternate Webpage(s) | https://doi.org/10.22465/kjuo.2018.16.3.119 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
