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Auswirkungen der Ultrafiltration auf die Lungenfunktion bei Kindern nach Korrektur eines angeborenen Herzfehlers
| Content Provider | Semantic Scholar |
|---|---|
| Author | Richter, Jost Wigand |
| Copyright Year | 2001 |
| Abstract | The capillary leak, associated with cardiopulmonary bypass in open heart surgery, causes a rise of total body water resulting in tissue, especially in pulmonary and myocardial edema. The modified ultrafiltration is a new aproach to reduce these edemas, first described by Naik, Knight and Elliot in 1991. With the modification of the postition of the ultrafilter in the bypass circuit and the time of filtration in the first minutes after the patient has been weaned from bypass a significant reduction of the bypass associated fluid accumulation could be shown as well as an improvement of hemodynamics (heart index, myocardial contractility, reduced need of inotopic drugs). To investigate the influence of the modified ultrafiltration on the lung function is the objective of this study. In this study 37 children (aging from 3 days to 92 months, weighting from 3.1 to 21.3 kg) have been examined in cardiac surgery for moderate to severe congenital heart disease with the application of the cardiopulmonary bypass. The effect of modified ultrafiltration, which immediately started after being weaned from the cardiopulmonary bypass, was studied in 27 children, 10 children formed the controll population. In all patients alterations in pulmonary mechanics (dynamic compliance and resistance), in pulmonary function (alveolar-arterial difference of oxygen), in hemodynamics (arterial and central venous blood pressure, heart rate) and in blood values (hemoglobin, hematocrit) could be recorded at frequent intervals. The measurements were done before and after being weaned from bypass, after conclusion of the |
| File Format | PDF HTM / HTML |
| DOI | 10.18452/14681 |
| Alternate Webpage(s) | https://edoc.hu-berlin.de/bitstream/handle/18452/15333/Richter.pdf?isAllowed=y&sequence=1 |
| Alternate Webpage(s) | http://edoc.hu-berlin.de/dissertationen/richter-jost-wigand-2001-12-14/PDF/Richter.pdf |
| Alternate Webpage(s) | https://doi.org/10.18452/14681 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
