NDLI: Concentração plasmática de 25 hidroxivitamina D em mulheres na pós-menopausa com baixa densidade mineral óssea

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Concentração plasmática de 25 hidroxivitamina D em mulheres na pós-menopausa com baixa densidade mineral óssea

Content Provider	Semantic Scholar
Author	Russo, Luis Augusto Tavares Gregório, Luiz Henrique De Lacativa, Paulo Gustavo Sampaio Marinheiro, Lizanka P. F.
Copyright Year	2009
Abstract	Objectives:This study was designed to determine mean serum concentrations of 25-hydroxyvita-min D (25OHD) in postmenopausal women with low bone mineral density (BMD), to find the cutoff of parathormone (PTH) elevation, and to evaluate the correlation 25OHD with BMD, biochemical parameters and vertebral fracture presence.Methods: Transversal study, with collection of 25OHD and PTH, and determination of DMO and column radiograph.Results: A high incidence of inade-quate serum concentrations of 25OHD (68.3%) was found and 8% of secondary hyperparathyreoi-dism. No significant differences were found between 25OHD serum concentrations and the evalu-ated parameters, except for PTH, which showed a negative association. The established cutoff was 61.5 nmol/L. Conclusions: The elevated incidence of hipovitaminosis D in elderly women with low BMD suggests that a systematic evaluation of 25OHD serum concentrations must be done for this population. The use of 61.5 nmol/L as a cutoff is recommended until the realization of an epidemio-logic study that represents all Rio de Janeiro city (RJ, Brazil).
Starting Page	1079
Ending Page	1087
Page Count	9
File Format	PDF HTM / HTML
DOI	10.1590/s0004-27302009000900004
Volume Number	53
Alternate Webpage(s)	http://www.scielo.br/pdf/abem/v53n9/v53n9a04.pdf
Alternate Webpage(s)	https://doi.org/10.1590/s0004-27302009000900004
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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