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On-chip colorimetric biosensor based on polydiacetylene (PDA) embedded in photopolymerized poly(ethylene glycol) diacrylate (PEG-DA) hydrogel
| Content Provider | Semantic Scholar |
|---|---|
| Author | Lee, Nae Yoon Jung, Yun Kyung Park, Hyun Gyu |
| Copyright Year | 2006 |
| Abstract | We have developed a new strategy to construct a colorimetric biosensor on a miniaturized platform. Polydiacetylene (PDA), which is widely known to change color by external stimuli, was employed as a sensing material. To construct a gel-based portable colorimetric biosensor using PDA, PDA was incorporated into poly(ethylene glycol) (PEG)-based hydrogel upon photopolymerization and PDA-embedded PEG hydrogel matrix was patterned within PDMS-based microfluidic channels. The resulting intrachannel hydrogel matrix containing PDA was reacted with -cyclodextrin as a model target sample, which causes a color change of PDA from blue to red. Parallel analyses were performed inside microchannels for multiple solutions containing different amounts of -cyclodextrin and color change gradients were successfully demonstrated depending on the contacting time and amount of -cyclodextrin. © 2005 Elsevier B.V. All rights reserved. |
| Starting Page | 103 |
| Ending Page | 108 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.bej.2005.02.025 |
| Alternate Webpage(s) | http://koasas.kaist.ac.kr/bitstream/10203/19929/1/On-chip%20colorimetric%20biosensor%20based%20on%20polydiacetylen(PDA)%20embedded%20in%20photopolymerized%20poly(ethylene%20glycol).pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.bej.2005.02.025 |
| Volume Number | 29 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
