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Occurrence of Plasmid-mediated AmpC β-lactamases among Enterobacter cloacae, Serratia marcescens and Citrobacter freundii in China
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cheng, Jingwei Sun, Jinyu |
| Copyright Year | 2016 |
| Abstract | Background: A total of 775 consecutive non-duplicate isolates of Enterobacteriaceae (534 E. cloacae, 137 S. marcescens and 104 C. freundii) were collected from 2005 to 2014 at 34 hospitals in Anhui Province, China. Material and Methods: The detection of plasmid-mediated AmpC β-lactamases (pAmpCs) was based on the inhibitor screening method. Then, the association with other β-lactamases and mobile genetic elements, like class 1 integron, ISCR1 and ISEcp1, were analyzed by molecular biology method. Results: Among the total of 775 isolates, the prevalence of pAmpC was discovered to be 8.1% (63/775) overall. In this study, the presence of pAmpCs was significantly linked to other β-lactamases and mobile genetic elements, among which blaCTX-M and class 1 integron were the most prevalent genotype. Conclusion: Therefore, various combinations of β-lactamases and mobile genetic elements were detected in the study. Plasmids were demonstrated to be the main vehicles for the dissemination of pAmpC genes. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.mona.uwi.edu/fms/wimj/system/files/article_pdfs/cheng20et20al-pampc20ceb2-lactamases20in20enterobacteriaceae1.pdf |
| Alternate Webpage(s) | https://doi.org/10.7727/wimj.2016.190 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |