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Combination of sodium stibogluconate and rifampicin in post kala-azar dermal leishmaniasis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sharma, Vinod Kumar Prasad, Harini Ram Sethuraman, Gomathy Khaitan, Binod Kumar |
| Copyright Year | 2007 |
| Abstract | Sir, Sodium stibogluconate (SSG) is the standard drug used for the treatment of post kala-azar dermal leishmaniasis (PKDL) at a dose of 20 mg/kg/day (maximum 850 mg/day) for at About six patients completed the treatment as one of the patients developed leucopenia while the other was lost to follow up after 56 days. Five of them had an excellent response. The onset of the response was noted as early as 1 week and all the five patients had started responding by 3 weeks of therapy. Facial lesions healed completely in all cases by 3 months. The hypopigmented macules repigmented completely in three patients [Figure 1]. The patient who was lost to follow-up after 56 days of therapy had 90% reduction in the facial lesions and 50% reduction in genital lesions. No recurrence was noted in the five patients who had an excellent response after a mean follow up period of 12 months (range 2 to 30 months). |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://tspace.library.utoronto.ca/bitstream/1807/47865/1/dv07017.pdf |
| PubMed reference number | 17314452v1 |
| Volume Number | 73 |
| Issue Number | 1 |
| Journal | Indian journal of dermatology, venereology and leprology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Antimony Sodium Gluconate Leukopenia Macule Milligram per Kilogram per Day Patients Post Kala-Azar Dermal Leishmaniasis Sodium Stibogluconate mg/kg |
| Content Type | Text |
| Resource Type | Article |