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Meaning of visualizing retinal cone mosaic on adaptive optics images.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Jacob, Julie Pâques, Michel Krivosic, Valérie Dupas, Bénédicte Couturier, Aude Kulcsár, Caroline Tadayoni, Ramin Massin, P. Gaudric, Alain |
| Copyright Year | 2015 |
| Abstract | PURPOSE To explore the anatomic correlation of the retinal cone mosaic on adaptive optics images. DESIGN Retrospective nonconsecutive observational case series. METHODS A retrospective review of the multimodal imaging charts of 6 patients with focal alteration of the cone mosaic on adaptive optics was performed. Retinal diseases included acute posterior multifocal placoid pigment epitheliopathy (n = 1), hydroxychloroquine retinopathy (n = 1), and macular telangiectasia type 2 (n = 4). High-resolution retinal images were obtained using a flood-illumination adaptive optics camera. Images were recorded using standard imaging modalities: color and red-free fundus camera photography; infrared reflectance scanning laser ophthalmoscopy, fluorescein angiography, indocyanine green angiography, and spectral-domain optical coherence tomography (OCT) images. RESULTS On OCT, in the marginal zone of the lesions, a disappearance of the interdigitation zone was observed, while the ellipsoid zone was preserved. Image recording demonstrated that such attenuation of the interdigitation zone co-localized with the disappearance of the cone mosaic on adaptive optics images. In 1 case, the restoration of the interdigitation zone paralleled that of the cone mosaic after a 2-month follow-up. CONCLUSION Our results suggest that the interdigitation zone could contribute substantially to the reflectance of the cone photoreceptor mosaic. The absence of cones on adaptive optics images does not necessarily mean photoreceptor cell death. |
| Starting Page | 577 |
| Ending Page | 589 |
| Page Count | 13 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.ajo.2014.09.043 |
| PubMed reference number | 25284764 |
| Journal | Medline |
| Volume Number | 159 |
| Issue Number | 1 |
| Alternate Webpage(s) | http://www.inviewmedical.pl/wp-content/uploads/2015/08/2015.01-Am-J-Opht-Jacob-et-al-Meaning-of-visualizing-cones-with-AO.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.ajo.2014.09.043 |
| Journal | American journal of ophthalmology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |