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A glucose biosensor based on direct electrochemistry of glucose oxidase immobilized on nitrogen-doped carbon nanotubes.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Deng, Shengyuan Jian, Guoqiang Lei, Jianping Hu, Zheng Ju, Huangxian |
| Copyright Year | 2009 |
| Abstract | A novel biosensor for glucose was prepared by immobilizing glucose oxidase (GOx) on nitrogen-doped carbon nanotubes (CNx-MWNTs) modified electrode. The CNx-MWNTs membrane showed an excellent electrocatalytic activity toward the reduction of O(2) due to its diatomic side-on adsorption on CNx-MWNTs. The nitrogen doping accelerated the electron transfer from electrode surface to the immobilized GOx, leading to the direct electrochemistry of GOx. The biofunctional surface showed good biocompatibility, excellent electron-conductive network and large surface-to-volume ratio, which were characterized by scanning electron microscopy, contact angle and electrochemical impedance technique. The direct electron transfer of immobilized GOx led to stable amperometric biosensing for glucose with a linear range from 0.02 to 1.02 mM and a detection limit of 0.01 mM (S/N=3). These results indicated that CNx-MWNTs are good candidate material for construction of the third-generation enzyme biosensors based on the direct electrochemistry of immobilized enzymes. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.bios.2009.07.016 |
| PubMed reference number | 19683424 |
| Journal | Medline |
| Volume Number | 25 |
| Issue Number | 2 |
| Alternate Webpage(s) | http://sklac.nju.edu.cn/hxju/lunwenlunzhu/paper2009/295%20bb%20deng%20s.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.bios.2009.07.016 |
| Journal | Biosensors & bioelectronics |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
