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Determination of 11 hormones residues in chicken using QuEChERS sample preparation method with ultra performance liquid chromatography-tandem mass spectrometry.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yingjie, Lian Hang, Lin Sheng Qi, Zeng Dun-Ming, Xu Liyi, Lin Yu, Zhou Zhi-Qiang, Huang |
| Copyright Year | 2014 |
| Abstract | Objective A multi-residue testing method was developed for the simultaneous determination of 4 androgens, 3 progesterones and 4 glucocorticoids in chicken using QuEChERS sample preparation method with ultra performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS). Methods The homogenized sample extracted with ethyl acetate. The separation was performed on a phenomenex kinetex column by gradient elution after puring from dispersive-solid-phase extraction(d-SPE). The analysis of 11 analytes were operated by electrospray ionization mass spectrometry under the positive or negative mode using multiple reaction monitoring (MRM). Acetonitrile and water(containing 0.1% formic acid) were used as the mobile phase both in positive and negative. Results The correlation coeficients of calibration curves were 第 2期 连英杰, 等: QuEChERS/超高效液相色谱-电喷雾串联质谱法检测鸡肉中 11种激素类药物残留 385 over 0.991 in the corresponding concentration range. The average recoveries of the 11 analytes at three spiked concentration levels varied from 84.4% to 94.1% and the relative standard deviations(RSDs) varied from 7.5% to 12.5%. The limits of detection(LOD, S/N≥3) and quantitation(LOQ, S/N≥10) were 0.37~9.55 μg/kg and 1.11~28.65 μg/kg, respectively. Conclusion The real sample tests showed that the proposed method was simple, rapid, sensitive, reliable and cost-effective, and it was suitable for the simultaneous determination of hormones residues in chicken samples |
| Starting Page | 384 |
| Ending Page | 392 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| Volume Number | 5 |
| Alternate Webpage(s) | http://www.chinafoodj.com/ch/reader/create_pdf.aspx?falg=1&file_no=20131128003&quarter_id=2&year_id=2014 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
