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PET amyloid imaging: Implications for estimating risk of progression to Alzheimer's disease in individuals with mild cognitive impairment
| Content Provider | Semantic Scholar |
|---|---|
| Author | Lingler, Jennifer H. Butters, Meryl A. McDade, Eric Sereika, Susan M. |
| Copyright Year | 2015 |
| Abstract | criteria; differences between the best performing methods were not significant. In general, sharply-segmented GM segmentations outperformed broader ones. SPM vs Freesurfer had mixed tradeoffs. Reference regions using supratentorial WM were highly reliable but performed poorly on plausibility criteria. Cerebellar GM was outperformed by cerebellar WM, whole cerebellum, crus, and pons, which were all roughly equivalent. Methods with PVC were each better or not significantly worse than those without. Conclusions:Our results support the use of PVC, narrow GM-segmentation targets, and whole-cerebellum, cerebellum-WM, crus, or pons reference regions for SUVR calculations. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.jalz.2015.06.1798 |
| Volume Number | 11 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S155252601502035X |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S155252601502035X?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/j.jalz.2015.06.1798 |
| Journal | Alzheimer's & Dementia |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
