Prevalence of Human Papillomavirus ( HPV ) Genotypes and Multiple Infections in Routine Cervical Cancer Screening in a Spanish Regional Population

Content Provider	Semantic Scholar
Copyright Year	2014
Abstract	Cervical cancer is the second most common cancer in women worldwide and the most common cause of mortality in underdeveloped and developing countries [1,2]. Persistent infection with certain oncogenic high-risk (HR) types of Human Papillomavirus (HPV) is the required factor for the development of invasive cervical cancer and precursor lesions [3-6]. Overall, the prevalence and distribution of HPV infection in cervical lesions has been determined in many geographical regions of the world, this can vary depending on several factors including epidemiological differences in the populations studied and the methodology used for molecular detection and typing of HPV DNA [7]. Over 120 types of HPV have been classified as either low (LR-HPV) or high risk (HR-HPV), according to their oncogenic potential [8,9]. Within the high-risk genotypes, HPV types 16 and HPV 18 are most often associated with cancer and squamous intraepithelial lesion [5,6,10,11,12]. Nevertheless, the risk of neoplasia for other types of HPV as well as for multiple HPV infection has not yet been established.
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Alternate Webpage(s)	https://symbiosisonlinepublishing.com/microbiology-infectiousdiseases/microbiology-infectiousdiseases05.pdf
Language	English
Access Restriction	Open
Subject Keyword	Cervix carcinoma Classification Epidemiology Genotype HIV Infections Human Papillomavirus Infiltrating Cervical Carcinoma LR parser Neck Neoplasms Population Squamous intraepithelial lesion heart rate
Content Type	Text
Resource Type	Article