NDLI: Regulatory genes of simian immunodeficiency viruses from west African green monkeys (Cercopithecus aethiops sabaeus).

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Regulatory genes of simian immunodeficiency viruses from west African green monkeys (Cercopithecus aethiops sabaeus).

Content Provider	Semantic Scholar
Author	Jubier-Maurin, Véronique Sarni-Manchado, Pascale Veas, Francisco Vidal, Nathalie González Bibollet-Ruche, Frederick Durand, Jacques P. Galat-Luong, A. Cuny, Gérard
Copyright Year	1995
Abstract	The high seroprevalence of simian immunodeficiency viruses (SIVs) in African green monkeys (AGMs) without immunological defects in their natural hosts has prompted consideration of SIV-infected AGMs as a model of apathogenic SIV infection. Study of the molecular mechanisms of SIVagm asymptomatic infection could thus provide clues for understanding the pathogenesis of human immunodeficiency viruses. Regulatory genes could be candidates for genetic control of SIVagm apathogenicity. We have characterized Vpr, Tat, Rev, and Nef genes of two SIVagm strains isolated from naturally infected sabaeus monkeys captured in Senegal. The results provide further evidence that SIVagm from West African green monkeys is the most divergent class of AGM viruses, with structural features in long terminal repeat sequences and Vpr and Tat genes that distinguish them from viruses isolated from other AGM species (vervet, grivet, and tantalus monkeys).
File Format	PDF HTM / HTML
DOI	10.1128/jvi.69.11.7349-7353.1995
PubMed reference number	7474168
Journal	Medline
Volume Number	69
Issue Number	11
Alternate Webpage(s)	http://jvi.asm.org/content/69/11/7349.full.pdf
Alternate Webpage(s)	http://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_37-38/43613.pdf
Alternate Webpage(s)	https://doi.org/10.1128/jvi.69.11.7349-7353.1995
Journal	Journal of virology
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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