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CD40 ligand (CD154) does not contribute to lymphocyte-mediated inhibition of virulent Mycobacterium tuberculosis within human monocytes.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Larkin, Rhonda Benjamin, Christopher Hsu, Yen-Ming Li, Qing Wen Zukowski, Lynn Silver, Richard F. |
| Copyright Year | 2002 |
| Abstract | Human monocytes displayed increased expression of CD40 following infection with virulent Mycobacterium tuberculosis. Nevertheless, soluble CD40 ligand (CD40L; also designated CD154) had no effect on the intracellular growth of the organism. Restriction of the intracellular growth of M. tuberculosis by peripheral blood lymphocytes and antigen-specific CD4+ T-cell lines likewise was not reduced by blocking anti-CD40L monoclonal antibody 5c8. |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/IAI.70.8.4716-4720.2002 |
| PubMed reference number | 12117990 |
| Journal | Medline |
| Volume Number | 70 |
| Issue Number | 8 |
| Alternate Webpage(s) | http://iai.asm.org/content/70/8/4716.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1128/IAI.70.8.4716-4720.2002 |
| Journal | Infection and immunity |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |