NDLI: Perfusion CT to evaluate the effect of transluminal angioplasty on cerebral perfusion in the treatment of vasospasm after subarachnoid hemorrhage

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Perfusion CT to evaluate the effect of transluminal angioplasty on cerebral perfusion in the treatment of vasospasm after subarachnoid hemorrhage

Content Provider	Semantic Scholar
Author	Beek, Diederik Van De Rooij, W. J. Van
Copyright Year	2007
Abstract	INTRODUCTION Delayed ischemic neurologic deficits secondary to vasospasm are a major cause of morbidity and mortality after subarachnoid hemorrhage (SAH). Treatment of vasospasm after SAH is associated with complications, and reliable techniques for evaluating effects of treatment of vasospasm in such patients are warranted. We present the use of perfusion computed tomography (PTC) to evaluate the effect of transluminal percutaneous angioplasty in a with SAH and vasospasm-induced ischemia. METHODS Dynamic PCT with deconvolution produced maps of time-to-peak, mean transit time, regional cerebral blood flow, and regional cerebral blood volume, with a computerized automated map of the infarct and penumbra. CT scanners with quadruple detector array were used before and after angioplasty. RESULTS Before angioplasty and intraarterial papaverine, PCT showed normal to decreased cerebral blood flow and increased cerebral blood volume and mean transit time in the middle cerebral artery territory of the left hemisphere. After angioplasty and intraarterial papaverine, PCT showed normalization of perfusion parameters. CONCLUSION PCT can be a useful technique in monitoring angioplasty treatment effects in patients with vasospasm after SAH.
Starting Page	40
Ending Page	44
Page Count	5
File Format	PDF HTM / HTML
PubMed reference number	17356190
Volume Number	6
Journal	Neurocritical care
Language	English
Access Restriction	Open
Subject Keyword	Angioplasty Cerebral Blood Volume Cerebral Infarction Cerebrovascular Circulation Detectors Morbidity - disease rate Neurodegenerative Disorders Papaverine Patients Porphyria Cutanea Tarda S-Adenosylhomocysteine Structure of middle cerebral artery Subarachnoid Hemorrhage Vasospasm, Intracranial X-Ray Computed Tomography
Content Type	Text
Resource Type	Article

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