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Cows' milk protein-sensitive enteropathy: an important contributing cause of secondary sugar intolerance in young infants with acute infective enteritis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Boey, C. G. Sumithran, Eric Yadav, Manmohan Puthucheary, Savithri Devi |
| Copyright Year | 1979 |
| Abstract | The effect of cows' milk protein (CMP) on the mucosal disaccharidases was investigated in 23 infants with acute infective enteritis. Jejunal biopsies performed before and after cows' milk provocation were subjected to histological examination and to mucosal disaccharidase enzyme (lactase, sucrase, and maltase) analyses. After milk challenge, changes in mucosal histology were observed in 18 infants, in 17 of them the levels of all 3 mucosal disaccharidases were much reduced. 10 of these infants developed diarrhoea and, in 6, the stools were positive for reducing sugar. It is concluded that CMP has a deleterious effect on the jejunal mucosa of young infants recovering from infective enteritis, so that in the management of young infants with sugar intolerance secondary to infective enteritis, CMP and lactose should be excluded from the diet. |
| Starting Page | 39 |
| Ending Page | 43 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://adc.bmj.com/content/archdischild/54/1/39.full.pdf |
| PubMed reference number | 570376v1 |
| Volume Number | 54 |
| Issue Number | 1 |
| Journal | Archives of disease in childhood |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Acute inflammatory demyelinating polyneuropathy Alpha-glucosidase Anti-Infective Agents, Local Biopsy Contribution Cow's milk Crohn Disease Diarrhea Disaccharidases Enteritis Exclusion Feces Jejunum Lactase Lactose Milk Proteins Milk, Human Mucous Membrane Sugars |
| Content Type | Text |
| Resource Type | Article |