NDLI: Indice de rigidez arterial ambulatorio y péptido natriurético cerebral en pacientes hipertensos antes y después del tratamiento antihipertensivo

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Indice de rigidez arterial ambulatorio y péptido natriurético cerebral en pacientes hipertensos antes y después del tratamiento antihipertensivo

Content Provider	Semantic Scholar
Author	Tejedor, Camilo E. Palencia González, Ruth Azuaje Ayala, José Luis López Oberto, Carlos Vera, Mariflor
Copyright Year	2016
Abstract	Resumen Objetivo : Analizar los cambios del Indice de rigidez arterial ambulatorio y el Peptido Natriuretico cerebral tipo B, ( IRAA y BNP) en 52 pacientes hipertensos que asistieron a la consulta Cardio-metabolica del Hospital Militar Dr. Carlos Arvelo, Caracas, Venezuela, entre enero y junio del 2015, antes y despues del tratamiento antihipertensivo. Metodos : se realizo un ensayo clinico pareado, abierto, aleatorizado, donde los pacientes hipertensos de novo que cumplieron con los criterios de inclusion fueron asignados de forma aleatoria al grupo de trabajo. Se realizo seguimiento por tres meses posterior al inicio del tratamiento antihipertensivo. Se comparo la presion arterial media segun el MAPA, IRAA y BNP en el primer y tercer mes en el grupo para evaluar exito en alcanzar el control, asi como tambien, se analizo la frecuencia de complicaciones cardiovasculares y muerte durante el estudio. Resultados : se encontro diferencia significativa entre los valores de AASI y BNP antes y despues de 3 meses de tratamiento antihipertensivo (p= < 0,01) independientemente del tratamiento antihipertensivo utilizado en el grupo de estudio. Conclusion : El AASI y BNP mostraron ser modificables con el tratamiento antihipertensivo, y que esta modificacion se relaciona positivamente con los cambios de algunos de los parametros del MAPA, como la Carga, la Presion de Pulso y la Presion Arterial Sistolica. Abstract Objective : to analyze the changes of AASI and BNP in hypertensive patients attending the Cardio- metabolic consultation of Hospital Dr. Carlos Arvelo Military (Caracas, Venezuela) between January and June 2015, before and after antihypertensive treatment. Methods : this is a paired trial, open, clinical, randomized trial, where hypertensive patients recently diagnosed were randomly assigned to the study group. Monitoring was done three months after initiation of antihypertensive treatment. The mean blood pressure was compared according to ABPM, AASI and BNP from the first to the third month in the group to evaluate success in achieving control, and the frequency of cardiovascular complications and death during the study were also analyzed. Results : A significant difference was found between the values of AASI and BNP before and after 3 months of antihypertensive treatment ( p = <0,01) regardless of which antihypertensive treatment was used in the study group. Conclusion : The AASI and BNP were modified with antihypertensive treatment, and this change was positively related to changes in some parameters of the ABP Monitoring, such as Load, Pulse Pressure and Systolic. Blood Pressure.
File Format	PDF HTM / HTML
Volume Number	32
Alternate Webpage(s)	http://www.svmi.web.ve/ojs/index.php/medint/article/download/389/382
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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