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Factors Correlated With Hepatitis C and B Virus Infections Among Injecting Drug Users in Tehran, IR Iran
| Content Provider | Semantic Scholar |
|---|---|
| Author | Amin-Esmaeili, Masoumeh Rahimi-Movaghar, Afarin Razaghi, Emran Mohammad Baghestani, Ahmad Reza Jafari, Siavash Baba |
| Copyright Year | 2012 |
| Abstract | BACKGROUND In Iran, the number of injecting drug users (IDUs) has increased in recent years. The rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections among IDUs are reportedly high. OBJECTIVES The purpose of this study was to assess factors correlated with HCV and HBV infections among IDUs in Tehran. PATIENTS AND METHODS A cross-sectional study included 899 IDUs recruited from the community, drug treatment centers, and drop-in-centers. The study involved interviews conducted using an adapted version of the WHO Drug Injection Study Phase II (Version 2b) questionnaire and blood testing for the HCV antibody, hepatitis B surface antigen, and hepatitis B core antibody. A logistic regression model was used to identify independent factors correlated with HCV and HBV infections. RESULTS HCV infection was found to be primarily associated with female gender [odds ratio (OR) 5.0, 95% confidence interval (CI) 2.0-10.0)], unmarried status (OR 2.9, 95% CI 1.9-4.4), drug use for more than 10 years (OR 2.7, 95% CI 1.8-3.9), drug injection frequency of more than once per day (OR 2.6, 95% CI 1.6-4.2), history of imprisonment (OR 2.5, 95% CI 1.6-4.0)], and a history of shared injection needles in prison (OR 2.3, 95% CI 1.5-3.6). HBV infection was mainly correlated with a history of imprisonment (OR 1.9, 95% CI 1.4-2.7) and drug use for more than 10 years (OR 1.4, 95% CI 1.1-1.9). CONCLUSIONS Because a considerable number of IDUs in Iran are receiving reduction services, tailoring services for prevention of hepatitis infection are necessary. |
| Starting Page | 23 |
| Ending Page | 31 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| PubMed reference number | 22451840v1 |
| DOI | 10.5812/kowsar.1735143x.806 |
| Journal | Hepatitis monthly |
| Volume Number | 12 |
| Alternate Webpage(s) | http://ftp.ncbi.nlm.nih.gov/pub/pmc/e2/2d/hepatmon-12-23.PMC3298872.pdf |
| Alternate Webpage(s) | https://doi.org/10.5812/kowsar.1735143X.806 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Chemical and Drug Induced Liver Injury Confidence Intervals Drug abuser Epstein-Barr Virus Infections Females HIV Infections Hepatitis B Surface Antigens Hepatitis B Virus Hepatitis C Antibodies Hepatitis C virus Herpesvirus 1, Cercopithecine Murine sarcoma viruses Needle device Odds Ratio Patients Substance Abuse Detection |
| Content Type | Text |
| Resource Type | Article |
