NDLI: Multiple thrombotic occlusions of vessels after Russell's viper envenoming.

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Multiple thrombotic occlusions of vessels after Russell's viper envenoming.

Content Provider	Semantic Scholar
Author	Hung, D. S. Wu, Ming-Ling Deng, J. F. Yang, Dar-Yu Lin-Shiau, Shoei-Yn
Copyright Year	2002
Abstract	Systemic bleeding due to consumption coagulopathy and thrombocytopenia due to activation of procoagulants is the leading manifestation and cause of death in Russell's viper systemic envenoming. Thrombotic occlusion of the blood vessels is rare in cases of snakebite. In this report, two adult patients with Russell's viper systemic envenoming presented multiple cerebral infarctions, digital gangrenes and ischaemic organs in addition to typical clinical manifestations of bleeding diathesis and renal involvement. Our findings in these two special cases suggest that the venom-induced coagulopathy and endothelium damage, predisposed by toxin-induced vasoconstriction, might be the possible mechanism of multiple thrombotic vascular occlusions in systemic envenoming of Formosan Russell's viper.
Starting Page	728
Ending Page	733
Page Count	6
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.kingsnake.com/aho/pdf/menu6/hung2002.pdf
PubMed reference number	12427109v1
Volume Number	91
Issue Number	3
Journal	Pharmacology & toxicology
Language	English
Access Restriction	Open
Subject Keyword	Blood Coagulation Disorders Blood Vessel Cerebral Infarction Cessation of life Disease susceptibility Disseminated Intravascular Coagulation Gangrene Hemorrhage Liver damage Lupus Erythematosus, Systemic Obstruction Organ Patients Russell-Silver syndrome Snake Bites Thrombocytopenia Thrombosis Thrombotic Microangiopathies Vascular constriction (function) Venoms
Content Type	Text
Resource Type	Article

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