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Spectrophotometric Determination of Bisoprolol Using Methyl Orange as Reagent
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gudruman, Alina Diana |
| Copyright Year | 2012 |
| Abstract | A spectrophotometric method for the quantitative determination of bisoprolol was established based on the formation of an ion pair complex between bisoprolol and methyl orange, in acid medium, extractable in dichloroethane, with a maximum absorbance at 427 nm. The limit of detection (LoD) was 0.20 µg/mL and the limit of quantification (LoQ) was 0.66 µg/mL. The elaborated method was validated. Rezumat Pentru determinarea bisoprololului fumarat s-a dezvoltat o metodă spectrofotometrică, bazată pe formarea unui complex de tip perechi de ioni intre bisoprolol si metil orange in mediu acid, extractibil in dicloretan, cu un maxim de absorbţie la 427 nm. Limita de detecţie (LD) a fost de 0,20 µg/mL, iar limita de cuantificare (LC) a fost 0,66 µg/mL. Metoda elaborată a fost validată. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.revistafarmacia.ro/201205/art5.gudruman.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |