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Computational Approaches Towards Drug Repositioning by Combining Heterogeneous Network Model and Random Walk Algorithm for Medicationsin NeurologicalDisorders
| Content Provider | Semantic Scholar |
|---|---|
| Author | Nair, Bipin |
| Copyright Year | 2018 |
| Abstract | Available drug information including the drug disease relationships are collected from data sources like Drug Bank, ChEMBL etc. A heterogeneous network is formed using collected data set of drugs and diseases from various data sources.Relationships among the elements in the network are identified. Random walk algorithm is applied in the two layer drug-disease network to identify new potential targets for existingdrugs.A combined approach of Heterogeneous Network model and Random walk algorithm on this network was able to identify new potential targets for existing drugs. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://acadpubl.eu/jsi/2018-118-18/articles/18e/61.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |