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Hypoglycemic and Antihyperglycemic Effect of Argyreia speciosa Sweet. in Normal and in Alloxan Induced Diabetic Rats
| Content Provider | Semantic Scholar |
|---|---|
| Author | Latha, E. Hema Satyanarayana, Tulasi Ramesh, Alluri Prasad, Y. V. K. Durga Routhu, Kasi Viswanath Srinivas, Ravipati A. |
| Copyright Year | 2008 |
| Abstract | Objective: To investigate the hypoglycemic and antihyperglycemic activities of methanolic extract of stem of Argyreia speciosa Sweet ( A. speciosa ) in normal and alloxan induced diabetic rats. Materials and method: The blood glucose levels were measured at 0 h and 1, 2, 4, 6, 8, 12, 16 and 24 h after the treatment. Oral glucose tolerance test was performed in normal, diabetic control, plant extract treated normal and diabetic groups and tolbutamide also treated normal and diabetic groups. Results: The alcoholic extract of A. speciosa showed significant (P<0.05) dose dependent percentage blood glucose reduction in normal (26.42% at 250 mg/kg, 28.50% at 500 mg/kg and 34.25% at 750 mg/kg body weight) and in diabetic rats (24.72% at 250 mg/kg, 31.10% at 500 mg/kg and 40.47% at 750 mg/ kg body weight) respectively at 8 h. Conclusion: The hypoglycemic and antihyperglycemic effect of A. speciosa was compared with the reference standard drug tolbutamide (40 mg/kg). |
| Starting Page | 203 |
| Ending Page | 208 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.18311/jnr/2008/334 |
| Volume Number | 8 |
| Alternate Webpage(s) | http://www.i-scholar.in/index.php/jnr/article/download/27858/24111 |
| Alternate Webpage(s) | https://doi.org/10.18311/jnr%2F2008%2F334 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
