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Enviro-economic , Ultrasound-assisted One-pot , Three-component Synthesis of Pyrido [ 2 , 3-d ] pyrimidines in Aqueous Medium
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hussein, Essam M. |
| Copyright Year | 2012 |
| Abstract | Tetra-n-butyl ammonium bromide (TBAB) was found to be an efficient phase-transfer catalyst for the synthesis of pyrido[2,3-d]pyrimidines by one-pot reaction of 6-aminouracils, aromatic aldehydes, and malononitrile or ethyl cyanoacetate in water under ultrasonic irradiation. The advantages of this method are the use of an inexpensive and readily available catalyst, short reaction time, easy work-up, improved yields, and the use of water as a solvent that is environmentally benign. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.znaturforsch.com/s67b/s67b0231.pdf |
| Alternate Webpage(s) | http://www.znaturforsch.com/ab/v67b/67b0231.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | AROMATICS Aldehydes Aromatic-L-Amino-Acid Decarboxylases Bromides Marijuana Abuse Pyrimidines Ultrasonics (sound) dicyanmethane ethyl cyanoacetate work up |
| Content Type | Text |
| Resource Type | Article |