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Effect of collagen on wave velocity in bone measured by micro-Brillouin scattering Brillouin
| Content Provider | Semantic Scholar |
|---|---|
| Author | Tsubota, Ryo Matsukawa, Mami Saito, Mitsuru Marumo, Keishi |
| Copyright Year | 2013 |
| Abstract | The diabetic disease and adynamic bone disease weaken bone, although the bone structure and bone mineral density (BMD) appear normal [1,2]. Therefore, U.S. National Institutes of Health (NIH) consensus development panel has pointed out the necessity to evaluate not only BMD but also bone quality. The ambiguous term “bone quality” includes several possible features of bone such as microto macroscopic structure, bone turnover, and material properties which affect bone elasticity. In order to retrieve bone elastic properties, quantitative ultrasound (QUS) methods in the MHz range have been used in vivo. Moreover, previous studies have shown that QUS is useful for the assessment of osteoporosis using speed of sound and broadband ultrasound attenuation. However, these parameters are affected by structure, heterogeneity and material properties in the large area through which the ultrasound waves passed. On the other hand, evaluating the mechanical properties of the bone without the effect of the microstructure remains difficult. In this study, using micro-Brillouin scattering technique with high spatial resolution, we measured wave velocity in the cortical bone. Focusing on the collagen especially, we estimate the relationship between wave velocity and the effect of water in bone. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.use-jp.org/proceedings/USE13/pdf/3P5-28.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
