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How breast cancer cells become more aggressive in response to targeted therapies
| Content Provider | Semantic Scholar |
|---|---|
| Copyright Year | 2020 |
| Abstract | As breast cancer develops, tumor cells begin to breach the tissue compartment that normally confines the mammary gland and actively invade and spread into the surrounding tissue. The research team, led by Dr. Christina Scheel attempted to block this process by exposing cancer cells to a small-molecule inhibitor targeting the TGF-beta Receptor Type I (TGFBR1). TGFBR1 is a crucial relay-protein in a signaling cascade known to endow breast cancer cells with the ability to invade. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://medicalxpress.com/pdf380964264.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |