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Characterization of phosphatidylinositol (3,4,5)-trisphosphate subcellular localization during endocytosis in Entamoeba histolytica
| Content Provider | Semantic Scholar |
|---|---|
| Author | Byekova, Yevgeniya A. |
| Copyright Year | 2008 |
| Abstract | ii DEDICATION iv ACKNOWLEDGEMENTS v LIST OF FIGURES xi CHAPTERS 1. LITERATURE REVIEW 1 Entamoeba histolytica 1 Background and Epidemiological Significance 1 Transmission and Pathogenesis 3 Diagnosis and Treatment 4 Endocytosis as Important Virulence Function: 6 Pinocytosis 6 Bacterial uptake and virulence 9 Apoptotic host cell killing and phagocytosis 10 Erythrophagocytosis 11 Molecular Mechanisms of Phagosome Biogenesis 14 Phosphoinositide-based signaling 19 Phosphatidylinositol derivatives as second messenger lipids 19 PI3-kinase family: products and inhibitors 21 PTEN and SHIP phosphatases as regulators of PIs cellular pool 24 Proteins with specific lipid-recognizing domains: 27 Pleckstrin homology (PH) domains: binding specificity and affinity 27 PH-domain containing proteins in E. histolytica as putative effectors of PIP3 29 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://tigerprints.clemson.edu/cgi/viewcontent.cgi?article=1404&context=all_theses&httpsredir=1&referer= |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |