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Whole-brain CBF measurements using DCE-MRI and 3 D kt PCA
| Content Provider | Semantic Scholar |
|---|---|
| Author | Pedersen, H. Hansen, Adam E. Larsson, Henrik B. W. |
| Copyright Year | 2010 |
| Abstract | INTRODUCTION: T1-weighted dynamic contrast enhanced (DCE) MRI has emerged as a promising technique for quantifying cerebral blood flow (CBF) and other vascular properties [1,2]. However, the clinical feasibility of DCE-MRI perfusion imaging is currently limited by low SNR and poor spatial coverage. To overcome these problems the data acquisition needs to be extended from current 2D techniques to a true 3D volumetric approach. This in turn requires a dramatic acceleration of the data acquisition in order to maintain sufficient temporal resolution to quantify CBF. The recently proposed k-t PCA technique [3] allows a considerable data reduction in dynamic MRI by jointly exploiting the separation of the aliased signals in x-f space [4] and the sparsity of dynamic data when subjected to principal component analysis (PCA). In this study we investigated the quality of whole-brain CBF measurements using 3D k-t PCA. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://cds.ismrm.org/protected/11MProceedings/files/785.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
